an early and cost effective way to detect lung cancer

Our focus is the early detection of lung cancer because of the high false positive rates associated with low dose CT scans
The problem

Lung Cancer is one of the most common cancers in the world

There were more than 2 million new cases in 2018. The majority of lung malignancies have already spread by the time they are diagnosed.

CT scanning currently has a false positive rate of approximately 90%, depending on route of referral. False positive results lead to unnecessary and costly investigations that are typically repeated multiple times. These are often invasive and can cause significant patient trauma.

False positive results lead to unnecessary, costly and invasive investigations and can cause significant patient trauma, and which are typically repeated multiple times.

There is currently no single biomarker blood-based diagnostic approved for use in the NHS for detection of lung cancer at an early stage

The solution

a new lung cancer test

Cizzle Biotech has developed a prototype confirmative test to address the false positive rates of CT scanning to avoid unnecessary invasive testing and costs

The test is intended to address a clear unmet clinical need – the early detection of lung cancer, when curative surgical resection is possible.

Initial product is intended to be an immunoassay for hospitals and reference laboratories. Follow on product could be a point of care test performed by a primary health care provider.


advantages to patients

+ Less radiation

Reduced exposure to radiation due to a reduced need for repeated CT scanning

+ Non-invasive

Relatively non-invasive, involving a small blood sample

+ Convenient

Will not require attending specialist scanning units within hospitals

+ Faster

Reduced waiting times until diagnosis


advantages to the healthcare system

+ Freeing up resources

Reducing burden on fixed resources, by freeing up CT scanners

+ Non-invasive

The test could allow for fewer patients needing costly, ultimately futile interventions