Significant Shareholders

01

Shareholder Information

Cizzle Biotechnology Holdings plc‘s shares are traded on the Standard Segment of the Main Market of the London Stock Exchange.
The Cizzle Biotechnology ticker code is CIZ

02

As at 10 December 2024, as far as the Directors are aware, the following shareholders have a significant interest in the issued share capital of the Company.

Hargreaves Lansdown (Nominees) Limited

92,857,577

23.43

Interactive Investor Services Nominees Limited

53,419,347

13.48

HSDL Nominees Limited

33,781,787

8.52

Yorkshire Cancer Research

32,382,330

8.17

Barclays Direct Investing Nominees Limited

20,250,228

5.11

Dawn Coverley *

17,048,137

4.30

HSBC Global Custody Nominee (UK) Limited

14,749,977

3.72

The Bank of New York (Nominees) Ltd

13,083,292

3.30

03

Legends

*this includes 7,055,548 shares which are held by Dawn Coverley’s husband, Justin Ainscough, a founder scientist of Cizzle Biotechnology